Publications by authors named "D Koulenti"

The isolation of may be related to comorbidity, prolonged mechanical ventilation, and survival during intensive care unit (ICU) stay, especially with non-albicans (NAC). To examine the frequency of isolation, associated comorbidities and outcomes in the surgical ICU in Osijek University Hospital, Croatia, the data from the electronic database from May 2016 to 30 June 2023 were analyzed. In a cross-sectional study examining 15,790 microbiological samples, different strains of were observed in 581 samples from 236 patients.

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Article Synopsis
  • The D-PRISM study investigated global practices for diagnosing and treating pneumonia in ICU settings, focusing on community-acquired, hospital-acquired, and ventilator-associated pneumonia across different countries.
  • A survey gathered responses from 1,296 ICU clinicians across 72 countries, revealing varied diagnostic processes and a lack of standardized microbiological testing, particularly in lower-income regions.
  • Findings indicated that the typical antibiotic treatment duration was 5-7 days, with shorter durations linked to effective antimicrobial stewardship programs in higher-income countries.
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During the COVID-19 pandemic, changes occurred within the surgical patient population. An increase in the frequency of resistant Gram-negative bacteria has since been recorded worldwide. After the start of the COVID-19 pandemic, microbiological diagnostics in our institution was performed using MALDI-TOF mass spectrometry.

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  • The study analyzed intra-abdominal infections (IAI) in immunocompromised versus non-immunocompromised ICU patients using data from the "AbSeS" database, which included 2,589 patients across 309 ICUs in 42 countries.
  • Immunocompromised patients (9.2% of the cohort) showed different infection patterns, such as more frequent typhlitis and a higher incidence of healthcare-associated infections, but had similar mortality rates compared to immunocompetent patients (31.1% vs. 28.9%).
  • Key risk factors for mortality in immunocompromised patients included septic shock at presentation and ongoing inflammation after source control, indicating that despite presenting with more severe conditions
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