Publications by authors named "D Konkle-Parker"
Background: In the US, Women, especially Black and Latina women living in disadvantaged environments, are disproportionally affected by HIV. Women living with HIV (WLHIV) have higher rates of suboptimal antiretroviral therapy (ART) adherence, and detectable viral load (VL). Experiences of intersectional poverty, HIV, gender, and racial stigmas may increase the rates of detectable VL through suboptimal ART adherence.
View Article and Find Full Text PDFThis study examined the association between cognitive intra-individual variability (IIV), a non-mean-based indicator of underlying neuropathology, and self-reported everyday functioning of 1,086 women with HIV (WWH) and 494 socio-demographically similar women without HIV (WWoH). Objective cognitive performance across seven domains and the self-rated Lawton & Brody scale of Instrumental Activities of Daily Living (IADL) were assessed among participants of the Women's Interagency HIV Study. Two types of cognitive IIV were calculated by taking the standard deviation across seven cognitive domains to calculate dispersion: 1) intra-individual standard deviation (denoted as IIV) and 2) coefficient of variation (denoted as IIV).
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- Socioeconomic status (SES) affects the well-being of people living with HIV (PWH), and using area-level SES indicators can help when individual data isn't available.
- ZIP code-level SES indicators were found to relate to viral suppression rates, and racial disparities in viral suppression narrowed by 3%-4% when accounting for SES factors.
- This study suggests that including ZIP code-based SES can enhance understanding of how social determinants and racial disparities impact health outcomes for PWH.
Article Synopsis
- A study investigated long-term body weight changes in people with HIV (PWH) who switched to antiretroviral therapies containing integrase strand-transfer inhibitors (INSTIs), comparing them with those on non-INSTI therapies and people without HIV (PWOH).
- The analysis included 3464 participants and revealed that women experienced significantly greater weight gain and increases in hip and thigh circumference after switching to INSTIs compared to men, with women gaining +3.0 kg and men +1.8 kg over 5 years.
- The findings suggest a 2-fold higher weight change in women versus men following the switch to INSTIs, although the long-term health implications of this difference are still uncertain.
Article Synopsis
- The study investigates how substance use impacts menopausal symptoms in people living with and without HIV in the US over a 12-year period.
- Data from the Women’s Interagency HIV Study involved self-reported information on menopausal symptoms, substance use, and demographic data analyzed using logistic regression.
- Findings reveal that current heavy alcohol, cumulative tobacco, and marijuana use are linked to increased frequency of vasomotor symptoms, while heavy alcohol and opioid use are associated with mood symptoms, highlighting the need for targeted interventions during menopause.