[Influence of Macular Hole Width on Visual Acuity, Endotamponade and Closure Rate].

The influence of the width of a full-thickness macular hole on preoperative visual acuity and its role for the intraoperative approach and closure rate were analysed in a prospective study. For 47 patients with a full thickness macular hole, a precise analysis of the central retina was performed with SD-OCT. An SF-gas-air mixture was used, with a lower concentration (15 %) for smaller holes ≤ 400 µm (group 1, n = 17) and a higher concentration (30 %) for larger holes > 400 µm (group 2, n = 30).

[Surgical treatment of chronic macular oedema with a combination therapy].

Background: The treatment of therapy-resistent chronic macular oedema remains a challenge. Therefore a combination therapy, consisting of medical, biological and mechanical components was assessed.

Methods: A surgical treatment was performed in 35 eyes (34 patients) with chronic and therapy-resistant macular oedema, resulting from diabetic maculopathy (n = 25), vitreoretinal traction (n = 7) or following a retinal venous occlusion (n = 3).

Glutamatergic neurotransmission in the first retinal synapse mediated by metabotropic receptors--electroretinographic study.

Aim: The aim of this study was to better characterize glutamatergic synaptic transmission between photoreceptors and retinal ON-bipolar cells. For this purpose we investigated the effect of L-serine orthophosphate (L-SOP) (an agonist of the group III metabotropic receptors) on the mass (electroretinographic) response of the ON-bipolar cells, which was obtained by isolated stimulation of the rods or the cones.

Materials And Methods: Isolated frog eyecup preparations (Rana ridibunda) were subjected to perfusion with L-SOP solution in various concentrations--10, 30, 100, 300, 500 and 1000 micromol/l.

[Orbital lymphoma].

Introduction: Orbital lymphomas are neoplasms with increasing incidence in recent years in immunocompromised, as well as immunocompetent patients, which defines their social importance.

Aim: To describe and analyze the experience of the University hospital "'Sv. Ivan Rilski" with the treatment of this pathology for the period 1997-2008.

Quantitative expediency assessment of the zeta sedimentation ratio and the plasma viscosity in arterial hypertension research.

Accepted methods of the ESR methodology (the Westergren mode and ZSR mode) and its alternative the plasma viscosity were tested for diagnostic utility in pregnancy induced hypertension and pre-eclampsia. The receiver-operating characteristic curve (ROC) analysis approved moderate diagnostic accuracy for the ESR methodology and supplied support for its preliminary estimated cutoff values but failed to indicate cogent discernment of pathology by values of plasma viscosity. Likely pathological whole blood alterations boost the erythrocyte aggregation while the concomitant depletion of macromolecules degrades plasma viscosity values.