Vitreoretinal findings similar to retinopathy of prematurity in infants with compound heterozygous protein S deficiency.

Objective: To present previously undescribed vitreoretinal findings similar to severe retinopathy of prematurity (ROP) in two siblings (daughter and son) with a thrombophilic disorder, compound heterozygous protein S (PS) deficiency.

Design: Family genotype study and literature review.

Participants: Two unrelated heterozygous PS-deficient parents and their two children with compound heterozygous PS deficiency were studied.

A small foveal avascular zone may be an historic mark of prematurity.

Objective: To compare in children the area and diameter of the foveal avascular zone (FAZ) of former preterm infants, when no significant retinopathy of prematurity (ROP) developed, to the area and diameter of the FAZ of former term infants.

Design: Retrospective observational case series and literature review.

Participants: Forty-nine children (39 former preterm infants and 10 former term infants) between the ages of 1 and 17 years had fluorescein angiograms.

Intraocular lenses in children: changes in axial length, corneal curvature, and refraction.

Aim: To assess changes in axial length, corneal curvature, and refraction in paediatric pseudophakia.

Methods: 35 eyes of 24 patients with congenital or developmental lens opacities underwent extracapsular cataract extraction and posterior chamber intraocular lens implantation. Serial measurements were made of axial length, corneal curvature, objective refraction, and visual acuity.

Refractive outcome in eyes with retinopathy of prematurity treated with cryotherapy or diode laser: 3 year follow up.

Aims: To compare the refractive error 1 to 3 years after cryotherapy or diode laser treatment for threshold retinopathy of prematurity.

Methods: Twenty six infants treated with diode laser and 17 infants treated with cryotherapy underwent cycloplegic refraction during follow up.

Results: After 3 years of follow up, 94.