Publications by authors named "D Kibirige"
Article Synopsis
- * A systematic review and meta-analysis were conducted, evaluating 15 studies that reported CKD prevalence, with findings showing a pooled prevalence of 12% but a wide variation among the studies (from 0.8% to 53.1%).
- * The analysis provided insights into the quality of the included studies and confirmed the robustness of the findings, showing no publication bias and identifying a significant degree of variability in CKD estimates.
Background: Efforts to eradicate tuberculosis (TB) are threatened by diabetes mellitus (DM), which confers a 3-fold increase in the risk of TB disease. The changes in the memory phenotypes and functional profiles of ()-specific T cells in latent TB infection (LTBI)-DM participants remain poorly characterised. We, therefore, assessed the effect of DM on T-cell phenotype and function in LTBI and DM clinical groups.
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- * It included 28 studies with data showing that Black Africans are generally younger, have a lower body mass index (BMI), but higher glycated hemoglobin levels compared to White Europeans.
- * The findings highlight significant ethnic differences in T2D manifestations, emphasizing the need for tailored management and prevention strategies that consider these differences.
Ethnic differences in the manifestation of early-onset type 2 diabetes.
BMJ Open Diabetes Res Care
August 2024
Introduction: We undertook phenotypic characterization of early-onset and late-onset type 2 diabetes (T2D) in adult black African and white European populations with recently diagnosed T2D to explore ethnic differences in the manifestation of early-onset T2D.
Research Design And Methods: Using the Uganda Diabetes Phenotype study cohort of 500 adult Ugandans and the UK StartRight study cohort of 714 white Europeans with recently diagnosed islet autoantibody-negative T2D, we compared the phenotypic characteristics of participants with early-onset T2D (diagnosed at <40 years) and late-onset T2D (diagnosed at ≥40 years).
Results: One hundred and thirty-four adult Ugandans and 113 white Europeans had early-onset T2D.
Background: Type 2 diabetes is common in relatively lean individuals in sub-Saharan Africa. It is unclear whether phenotypic differences exist between underweight and normal-weight African patients with type 2 diabetes. This study compared specific characteristics between underweight (body mass index <18.
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