Publications by authors named "D Kedar"
Diabetic foot ulcer represents the primary cause of hospital admissions, amputations, and mortality in diabetic patients. The development of diabetic foot ulcers is influenced by peripheral neuropathy, infection, and ischemia, with diabetes contributing to peripheral artery disease. Free tissue transfer combined with revascularisation of the lower extremity provides the potential opportunity for limb salvage in individuals with lower extremity defects due to critical limb ischemia and diabetic foot.
View Article and Find Full Text PDFIntroduction: organ cultures (EVOC) were recently optimized to sustain cancer tissue for 5 days with its complete microenvironment. We examined the ability of an EVOC platform to predict patient response to cancer therapy.
Methods: A multicenter, prospective, single-arm observational trial.
Article Synopsis
- A recent study examined the use of PASA16 phage therapy in 16 patients with stubborn Pseudomonas aeruginosa infections, highlighting the largest compassionate-use series of its kind.
- The phages were administered either intravenously or topically, showing good results in 13 out of 15 cases, with only minor side effects reported.
- The findings suggest that combining PASA16 with traditional antibiotics is a promising option for patients who haven't responded to standard treatments, paving the way for future clinical trials.
Effective cryopreservation of large tissues, limbs, and organs has the potential to revolutionize medical post-trauma reconstruction options and organ preservation and transplantation procedures. To date, vitrification and directional freezing are the only viable methods for long-term organ or tissue preservation, but are of limited clinical relevance. This work aimed to develop a vitrification-based approach that will enable the long-term survival and functional recovery of large tissues and limbs following transplantation.
View Article and Find Full Text PDFProstate-specific antigen level association with COVID-19 infection and vaccination.
Clin Genitourin Cancer
December 2023
Introduction: The associations among SARS-CoV-2 infection, vaccination and total serum prostate serum antigen (PSA) levels in men undergoing screening for prostate cancer are unknown.
Methods: A retrospective analysis of data from a large health maintenance organization. Records of individuals aged 50 to 75 years with two serum PSA tests taken between March 2018 and November 2021 were included.