Publications by authors named "D Keckarevic"
Article Synopsis
- The study aimed to validate a predictive model using Short Tandem Repeat (STR) profiles to determine ancestry affiliation among distinct population groups (African Americans, Asians, Caucasians, and Hispanic Americans) through machine learning.
- A total of 360,000 genetic profiles were created, with the XGBoost model proving to be the most accurate, achieving a 94.24% accuracy overall and even higher rates when differentiating specific subgroups.
- Results indicated that a larger training set size positively impacted accuracy, peaking at 94% with 90,000 profiles per category, while using a reduced number of markers still yielded relatively high accuracy, suggesting STR-based models could enhance forensic investigations involving ancestry.
Genetic structure of the contemporary Serbian population was shaped by a long history of turbulent historical and demographical events. The most important migrations of Serbs towards present day Serbia, in the recent history, occurred between the 15th to the 18th century from the regions of Old Herzegovina and Kosovo and Metohija. Previous haplogroup analysis revealed wide spectrum of main haplogroups, among which haplogroup I-P37.
View Article and Find Full Text PDFGenetic variability of Roma population was shaped by the strong influence of genetic drift and gene flow during the migrations from their ancestral homeland in Indian subcontinent towards Europe. In addition, social stigmatization in many European countries, as a consequence of different cultural heritage and social practices, induced further genetic differentiation and sub structuring within the population. Although many populations genetic studies on European Roma were carried out, the genetic structure of the Serbian Roma has not been described yet, since only the modest number of individuals from this territory was analyzed.
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- - The study monitored the evolution and emergence of SARS-CoV-2 variants in Serbia between March 2020 and January 2023, analyzing samples from 2,398 COVID-19-positive patients using advanced sequencing technologies.
- - Three major variants of concern were identified: Alpha (5.6%), Delta (7.4%), and Omicron (70.3%), with the Omicron recombinant known as "Kraken" (<1%), along with other sublineages contributing to eight pandemic waves in Serbia similar to trends observed in Europe and the U.S.
- - The research revealed a variety of mutations in the virus, particularly in the spike protein, with a total of sixteen Nextstrain clades being assigned to the samples
The rise and fall of the Roman Empire was a socio-political process with enormous ramifications for human history. The Middle Danube was a crucial frontier and a crossroads for population and cultural movement. Here, we present genome-wide data from 136 Balkan individuals dated to the 1 millennium CE.
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