Publications by authors named "D Karsenti"
Digestive endoscopy is a highly dynamic medical discipline, with the recent adoption of new endoscopic procedures. However, comprehensive guidelines on the role of antibiotic prophylaxis in these new procedures have been lacking for many years. The Guidelines Commission of the French Society of Digestive Endoscopy (SFED) convened in 2023 to establish guidelines on antibiotic prophylaxis in digestive endoscopy for all digestive endoscopic procedures, based on literature data up to September 1, 2023.
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- A multicenter study assessed the feasibility and safety of EUS-guided fiducial marker placement in patients with esophageal or rectal cancer referred for radiation therapy, focusing on success rates and outcomes.
- The study involved 33 patients, achieving a 93.9% success rate in marker placement, with an average procedure time of 12.5 minutes and no reported adverse events.
- Results showed that all fiducial markers remained visible throughout radiation therapy, emphasizing the approach's safety and effectiveness for these cancer types.
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- Missed lesions during colonoscopy can lead to post-procedure colorectal cancer, prompting the development of contrast-enhanced technologies like linked color imaging (LCI) for better polyp detection.
- A national, randomized trial compared polyp detection rates between standard white-light imaging (WLI) and LCI in the right colon, involving 764 patients across 10 endoscopy units.
- Results showed no significant difference in the proximal adenoma miss rate or miss rates for other types of lesions between the WLI-first and LCI-first groups, challenging the idea that LCI improves detection in routine colonoscopy.
Optimizing the adenoma detection rate (ADR) is a major goal in colorectal cancer (CCR) screening, as it has long been established that ADR is inversely proportional to the risk of post-colonoscopy CRC occurrence. To achieve this goal, many optimization devices have been developed, and numerous randomized controlled trials have been conducted to evaluate the benefits of these devices compared with a "standard arm," which corresponds to date to high-definition white light (HD-WLI) colonoscopy. Numerous studies have confirmed the positive impact of various optimization devices, such as caps, computer-aided detection, and contrast-enhanced technologies.
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