Publications by authors named "D Karassawa-Zanoni"
Article Synopsis
- Doctors usually check for oral cancer by looking at it and taking a small sample, but this can sometimes be wrong.
- A new method called PARPi-FL allows patients to gargle a special solution that lights up cancer cells, helping doctors see them better.
- In a study with 12 patients, this method was safe and showed clear differences between healthy tissue and cancer, making it a hopeful new way to detect oral cancer early.
Background: Distant metastases (DMs) are the primary cause of treatment failure in patients with salivary gland carcinoma. There is no consensus on the standard treatment.
Methods: Patients with DMs were identified from an institutional database of 884 patients with salivary gland cancer who underwent resection of the primary tumor between 1985 and 2015.
Accurate detection and quantification of metastases in regional lymph nodes remain a vital prognostic predictor for cancer staging and clinical outcomes. As intratumoral heterogeneity poses a major hurdle to effective treatment planning, more reliable image-guided, cancer-targeted optical multiplexing tools are critically needed in the operative suite. For sentinel lymph node mapping indications, accurately interrogating distinct molecular signatures on cancer cells in vivo with differential levels of sensitivity and specificity remains largely unexplored.
View Article and Find Full Text PDFBackground: This study aims to evaluate the impact of perioperative fluid administration, defined as fluid delivered intraoperatively and in the postanesthesia care unit, on postoperative outcomes.
Methods: Medical records of 102 patients with oral cavity squamous cell carcinoma undergoing free flap reconstruction between January 2011 and December 2015 were reviewed. The primary endpoint was development of a postoperative complication according to the Clavien-Dindo classification.