Dynamic Projection of Medication Nonpersistence and Nonadherence Among Patients With Early Breast Cancer.

Importance: Oral endocrine treatments have been shown to be effective when carefully adhered to. However, in patients with early breast cancer, adherence challenges are notable, with 17% experiencing nonpersistence and 41% nonadherence at least once.

Objective: To model the persistence of and adherence to oral anticancer treatment of a patient with localized breast cancer.

Methodology of phase II clinical trials in metastatic elderly breast cancer: a literature review.

Purpose: As the incidence of invasive breast cancer will increase with age, the number of elderly patients with a diagnosis metastatic breast cancer will also rise. But the use of cytotoxic drugs in elderly metastatic breast cancer patients is not systematic and is dreaded by medical oncologists. The need for prospective oncologic data from this population seems increasingly obvious.

External validation of a published nomogram for prediction of brain metastasis in patients with extra-cerebral metastatic breast cancer and risk regression analysis.

Background: Survival of patients with metastatic breast cancer (MBC) suffering from brain metastasis (BM) is limited and this event is usually fatal. In 2010, the Graesslin's nomogram was published in order to predict subsequent BM in patients with breast cancer (BC) with extra-cerebral metastatic disease. This model aims to select a patient population at high risk for BM and thus will facilitate the design of prevention strategies and/or the impact of early treatment of BM in prospective clinical studies.

Transperineal versus transvaginal ultrasound cervical length measurement and preterm labor.

Objective: The aim was to evaluate the agreement between and the reproducibility of transperineal and transvaginal ultrasound cervical length measurements performed by the duty obstetrical team in case of preterm labor. The acceptability of transperineal ultrasonography was also assessed.

Methods: Pregnant patients between 25 and 34 weeks of gestation with contractions and a clinically modified cervix were included.

Pelvic magnetic resonance imaging in the ewe: a model for experimental gynecologic research.

Aim: Our goal was to demonstrate the feasibility of pelvic magnetic resonance imaging (MRI) in the ewe.

Material And Methods: Two ewes underwent a pelvic 3 Tesla MRI scan, under light anesthesia, with T2-weighted fast spin-echo images and T1-weighted spoiled gradient-echo images. Multiplan T1 weighted images were also obtained after the intravenous injection of a contrast product.