Publications by authors named "D Kalthoff"

Low genomic diversity is generally indicative of small population size and is considered detrimental by decreasing long-term adaptability. Moreover, small population size may promote gene flow with congeners and outbreeding depression. Here, we examine the connection between habitat availability, effective population size (N), and extinction by generating a 40× nuclear genome from the extinct blue antelope (Hippotragus leucophaeus).

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argentina is the name that was given to describe a gray brocket collected by Lönberg in 1919 in the central Chaco region of Argentina. Subsequent authors, based on morphological similarities, considered this name to be a synonym for the species Fischer, 1814 from Paraguay. In the absence of genetic analyses to compare the Argentinian and Paraguayan gray brockets, we aimed to clarify the taxonomy of through an integrative assessment using morphological, cytogenetical, and molecular data from its holotype and a current topotype.

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  • The Dog10K project sequenced genomes from 1,987 canids, including 1,611 dogs of 321 breeds, to study genetics related to domestication and health.
  • The analysis identified over 48 million genetic variants and highlighted that most breeds exhibit strong genetic clustering, with German Shepherds showing notable genetic similarities with various breeds.
  • This extensive dataset enhances understanding of canine genetics and can be used as a reliable reference for future genetic studies, with all data now publicly accessible.
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  • The black rhinoceros is critically endangered, with its numbers drastically reduced due to hunting and poaching, particularly in the late 20th century.
  • Researchers conducted genomic studies on 63 historical black rhinoceros specimens to identify six major historic populations and their subpopulations, revealing significant genetic structure influenced by geographic barriers.
  • Findings from this genetic analysis provide insights for developing urgent management strategies aimed at conserving the remaining diversity of black rhinoceros populations.
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  • The blue antelope is the only large African mammal known to have gone extinct in recent history, with no complete genomic data previously available due to misidentifications of museum specimens.
  • Researchers successfully obtained two draft genomes: one from a historical specimen about 200 years old and another from a fossil dating back around 9,800 years, which is currently the oldest paleogenome known from Africa.
  • Genetic analyses reveal that blue and sable antelope are closely related, with evidence of past gene flow, while indicating low genetic diversity in blue antelope, which, along with fossil findings, points to significant population decline before the species' extinction, likely exacerbated by human impact during the colonial era.
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