Wide clinical implementation of insulin resistance syndrome?

The aim of this paper is to review the literature regarding the metabolic syndrome and the single factor that links all its core components. That single factor seems to be partial insulin deficiency (PID), which is responsible for varying degrees of atherosclerotic vascular damage. In conclusion, we found that the diagnosis of insulin resistance syndrome (IRS) may allow clinicians to diagnose and treat atherosclerosis at an early stage-to stop or reverse vascular damage.

[The influence of high levels of endogenous and exogenous insulin on the complications of type 2 diabetes and metabolic parameters].

The aim of our investigation was to study the influence of high levels of endogenous and exogenous insulin on the complications of type 2 diabetes and metabolic parameters. 62 patients with DM2 (mean age - 50,2+/-9,7 years) have been investigated. The parameters of carbohydrate metabolism, HOMA-indices, parameters of lipid metabolism, blood pressure, BMI and waist circumference have been determined.

[The relation of insulin resistance with the complications of diabetes mellitus type 2 and metabolic parameters].

The aim of our investigation was to study the relation of insulin resistance (IR) with the complications of diabetes mellitus type 2 (DM2) and metabolic parameters. 44 patients with DM2 (mean age - 49,1+/-8,7 years) have been investigated. The parameters of carbohydrate metabolism, HOMA-indices, parameters of lipid metabolism and blood pressure have been determined.

[Relation of serum uric acid levels with basic metabolic parameters in patients with metabolic syndrome during insulin-sensitizing therapy].

The aim of our investigation was to study the peculiarities of serum uric acid (UA) levels in patients with metabolic syndrome (MS) during 6 month therapy with metformin (MF), Rosiglitazone (RG) and their combination. 30 patients with MS (10 males, 20 females, mean age - 35,5+/-9,7 years) have been investigated by all parameters of MS and serum UA levels. Investigated group was divided into 3 subgroups of 10 patients: group 1 - patients on RG; group 2 - patients on MF; group 3 - patients on RG + 850-1000 mg of MF.

[The dependence of changes of parameters of metabolic syndrome features on the reduction of degree of insulin resistance during lifestyle intervention].

The aim of our investigation was to study the dependence of changes of parameters of metabolic syndrome (MS) features on the reduction of degree of insulin resistance during lifestyle intervention--balanced diet and moderate exercise. 33 patients with MS have been investigated (mean age--49.1+/-8.