Publications by authors named "D K Sasaki"
Article Synopsis
- The yips is a coordination issue in athletes, especially baseball players, tied to task-specific dystonia.
- This study focused on two baseball players displaying different yips symptoms, analyzing their throwing motions and muscle activity using advanced technology.
- It identified two types of dystonic movements: one involving excessive elbow flexion due to improper muscle contraction, and another featuring tremors from inconsistent muscle activity, emphasizing the need for personalized analysis in understanding and addressing yips symptoms.
Cardiac alternans (C-ALT) is a phenomenon of alternating strong and weak contractions in the heart and is considered a risk factor for the development of heart failure and arrhythmias. However, no model has been reported that can induce C-ALT in vitro using human cells, and the developmental mechanism of C-ALT has not been studied using human cells. In this study, we successfully induced C-ALT in vitro using human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs).
View Article and Find Full Text PDFObjective: To synthesize the available literature on myofascial manipulation interventions and adverse events to assess the knowledge gaps and select adaptations to determine the optimal approach.
Methods: PubMed, CINAHL, Web of Science, Embase, MEDLINE, and the Physiotherapy Evidence Database were searched from inception to December 11, 2022. This review included patients with musculoskeletal disorders, pain, and dysfunction.
Wild-type transthyretin amyloid (ATTRwt) deposits in most organs, mainly the heart, ligaments, and tenosynovium. Orthopedic diseases due to ATTRwt deposits often precede overt ATTRwt cardiomyopathy. 99mTc-PYP scintigraphy is highly sensitive in detecting myocardial and extracardiac ATTRwt deposits.
View Article and Find Full Text PDFArticle Synopsis
- Long-term use of subcutaneous insulin can cause tissue changes, like insulin amyloidosis, leading to issues with blood sugar control at the injection site.
- Insulin amyloidosis can result in nodules known as "insulin balls," which have not been previously studied using 99m Tc-PYP scintigraphy.
- A case is presented involving a 74-year-old man with diabetes who developed heart failure, and while cardiac scans showed no amyloidosis in the heart, they did reveal significant uptake related to an insulin ball.