Publications by authors named "D K Paramita"

Background: This study describes the seroconversion and serodynamics of IgG antibodies against the RBD of SARS-CoV-2 in the general population of Sleman District, Yogyakarta Special Province. We aim to identify possible factors that correlate with the seroconversion and serodynamics of IgG antibodies against the RBD of SARS-CoV-2.

Methods: We performed a longitudinal study of the population at Health and Demographic Surveillance System (HDSS) Sleman, Yogyakarta, Indonesia.

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Background: Chemotherapy has a substantial role in decreasing the risk of recurrence and mortality in breast cancer (BC) in a dose-dependent manner where a low relative dose intensity (RDI) is associated with unfavorable outcomes. Several baseline clinicopathological factors, including pro-inflammatory biomarkers, were found to be significant determinants of low RDI. This study aimed to explore the occurrence of low RDI and its influencing factors in women with BC.

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Article Synopsis
  • Chemotherapy-induced peripheral neuropathy (CIPN) negatively impacts the quality of life for breast cancer patients, leading to a study that aimed to develop a prediction model using the classification and regression tree (CART) algorithm.
  • The research involved 170 breast cancer patients and used a patient-reported assessment to identify CIPN occurrences, ultimately finding that high C-reactive protein (CRP) levels, BMI, and marital status are key predictors of CIPN.
  • The CART model achieved an accuracy of 65.9% and highlighted the importance of CRP levels and neutrophil-to-lymphocyte ratios in predicting CIPN, suggesting this model could be useful for developing individualized patient care strategies in the future.
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Inherited retinal dystrophy (IRD) is a group of phenotypes caused by mutations in visual pathways-related genes, mostly occurring at photoreceptors. This heterogeneous group includes retinitis pigmentosa (RP) recognised by bone spicule at the peripheral retina and the other is Stargardt with macular pisiform flecks. In this study, a 20- year-old male patient with RP symptoms was accompanied by a yellowish pisiform flex in the macula.

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Background And Purpose: Highly metastatic breast cancer is a population of cancer cells that has metastasized to other organs in the body leading to apoptosis resistance. It was reported that MDAMB-231 cells contain lower levels of reactive oxygen species associated with metastatic capability. (CL) possesses cytotoxic effects in several cancer cells including metastatic breast cancer cells.

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