Publications by authors named "D K Kephart"
Article Synopsis
- * Twelve children were involved, using different methods of neuraxial anesthesia, with their pain levels and opioid usage monitored.
- * Results showed effective pain control with minimal complications, indicating that neuraxial anesthesia is a viable option for these patients, especially using the ITB pump’s side port for opioid delivery when other methods are unsuitable.
Background: Our understanding of the biology of ankle arthrodesis is based largely on work in spine and long bone animal models. However, the local soft tissue and vascular anatomy of the foot and ankle is different from that of the spine. Accordingly, the objective of this study was to develop a small animal ankle arthrodesis model.
View Article and Find Full Text PDFBackground: School-based student health screenings identify issues that may affect physical and intellectual development and are an important way to maintain student health. Nonprofit hospitals can provide a unique resource to school districts by assisting in the timely completion of school-based screenings and meet requirements of the Affordable Care Act. This case study describes the collaboration between an academic medical center and a local school district to conduct school-based health screenings.
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- Podoplanin (PDPN) is a receptor that enhances the movement of tumor cells, making it a potential target for cancer treatment, especially in oral squamous cell carcinoma (OSCC).
- A study found that both a monoclonal antibody (NZ-1) and a lectin (MASL) targeting PDPN significantly reduced the migration of OSCC cells and eventually led to cell death through a specific necrosis process.
- The lectin MASL proved to be particularly effective, targeting PDPN quickly and reducing cancer spread in living organisms; this research suggests that both antibodies and lectins could be valuable in treating OSCC and similar PDPN-expressing cancers.
Sampling of agricultural and natural environments in two US states (Colorado and Florida) yielded 18 Listeria-like isolates that could not be assigned to previously described species using traditional methods. Using whole-genome sequencing and traditional phenotypic methods, we identified five novel species, each with a genome-wide average BLAST nucleotide identity (ANIb) of less than 85% to currently described species. Phylogenetic analysis based on 16S rRNA gene sequences and amino acid sequences of 31 conserved loci showed the existence of four well-supported clades within the genus Listeria; (i) a clade representing Listeria monocytogenes, L.
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