Publications by authors named "D K Hardesty"

Objective: The endoscopic endonasal approach (EEA) has evolved into an established technique in skull base surgery. The authors previously examined 1002 EEA procedures and reported factors associated with postoperative complications. Here they report the development and validation of a scoring model based on risk factors to better predict complications following EEA.

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Purpose: Advancements in endoscopic skull base surgery have enabled complex tumor resections, necessitating a variety of reliable reconstructive techniques to repair resultant defects. Vascularized flaps represent optimal options, but frequently used local pedicled intranasal flaps may be unavailable due to tumor invasion or prior surgery. This study applies a modification to the previously described salpingopharyngeus myomucosal flap (Dicle flap) with potential for its use in extensive endoscopic skull base surgery defect's repair.

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Article Synopsis
  • The study evaluates the effectiveness of the extended middle fossa approach (eMCF) for removing tumors in specific brain regions and compares outcomes for elderly versus younger patients.
  • A total of 29 patients were analyzed, with most tumors being meningiomas, and the majority of patients did not experience new cranial nerve deficits post-surgery.
  • Results indicate that the eMCF approach is safe and effective for elderly patients, showing no significant differences in complications or recovery compared to nonelderly patients.
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Article Synopsis
  • The formation of the RAPID initiative aims to improve research and quality in pituitary tumor treatment by establishing a collaborative platform among 11 academic U.S. centers and creating standardized data modules for various pituitary disorders.
  • The development process incorporated lessons learned from past challenges in creating research registries, ensuring that RAPID has a solid governance structure, including a Steering Committee and data coordination center.
  • RAPID is currently compiling both retrospective and prospective data and is looking to facilitate multicenter research that can lead to important studies on outcomes, biobanking, and health economics in the field of pituitary tumors.
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Objective: The expanded endonasal transpterygoid approach (EETA) is used to access the middle and posterior fossa through the pterygoid process. Traditionally, the eustachian tube (ET) was resected during EETA, which often required subsequent myringotomy for inner ear drainage. Anterolateral transposition of the ET was proposed to decrease potential morbidity associated with resection.

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