Tissue Cadherin 17 (CDH17): An Important Prognostic Determinant of Colorectal Cancer Using Digital Image Analysis.

Background: Colorectal cancer (CRC) is a commonly diagnosed malignancy with significant mortality rates worldwide. The identification of robust prognostic biomarkers for prediction of survival outcomes and recurrence can aid disease management and improve patients' quality of living.

Aim: This study aimed to investigate the prognostic value of cadherin 17 (CDH17) tissue expression in CRC patients by utilizing a standardized automated immunohistochemistry (IHC) platform integrated with a digitalized scoring system.

Effects of ambient temperature on mental and neurological conditions in older adults: A systematic review and meta-analysis.

Background: Emerging research has suggested a link between ambient temperature and mental and neurological conditions such as depression and dementia. This systematic review aims to summarize the epidemiological evidence on the effects of ambient temperature on mental and neurological conditions in older adults, who may be more vulnerable to temperature-related health effects compared to younger individuals.

Methods: A systematic search was conducted in PubMed, Ovid/Embase, Web of Science, and Ovid/PsycINFO on July 17, 2023, and updated on July 31, 2024.

Direct-to-consumer telemedicine in primary care settings: A scoping review of contemporary empirical literature.

Background And Objectives: This study comprehensively reviews the contemporary empirical literature on direct-to-consumer (DTC) telemedicine services within primary care.

Method: MEDLINE, Embase and SCOPUS were strategically searched and screened. Data on the modality of consultations, population of focus, condition of focus and treatment of focus were extracted, narratively synthesised and tabulated.

Temperature, Crime, and Violence: A Systematic Review and Meta-Analysis.

Background: Heat is known to affect many health outcomes, but more evidence is needed on the impact of rising temperatures on crime and/or violence.

Objectives: We conducted a systematic review with meta-analysis regarding the influence of hot temperatures on crime and/or violence.

Methods: In this systematic review and meta-analysis, we evaluated the relationship between increase in temperature and crime and/or violence for studies across the world and generated overall estimates.

Short-term effects of wildfire-specific fine particulate matter and its carbonaceous components on perinatal outcomes: A multicentre cohort study in New South Wales, Australia.

Background: Epidemiological evidence on the association between wildfire-specific fine particulate matter (PM) and its carbonaceous components with perinatal outcomes is limited. We aimed to examine the short-term effects of wildfire-specific PM and its carbonaceous components on perinatal outcomes.

Methods: A multicentre cohort of 9743 singleton births during the wildfire seasons from 1 September 2009 to 31 December 2015 across six cities in New South Wales, Australia were linked with daily wildfire-specific PM and carbonaceous components (organic carbon and black carbon).