Publications by authors named "D K Dube"
Article Synopsis
- - The ASM Curriculum Guidelines emphasize the importance of active learning in microbiology courses, suggesting that this approach promotes student participation and success, despite the temptation of resorting to traditional lectures in content-heavy courses.
- - A case series focusing on respiratory syncytial virus (RSV) was developed to boost student engagement by connecting various microbiology concepts through different learning objectives, utilizing methods like case-based learning and real-world data analysis.
- - Student feedback has shown that they prefer these interactive activities over typical lectures, as the case series helps them better understand and relate key microbiological concepts, fostering higher-order thinking and real-world application.
Previous reports from our laboratory describing the formation of myofibrils in cultured embryonic cardiac and skeletal muscle cells have proposed that myofibrillogenesis occurs in three steps of increasing protein organization: beginning with premyofibrils, followed by nascent myofibrils, and ending in mature myofibrils. Inhibitors of the ubiquitin proteasome system (UPS) prevented nascent myofibrils from progressing directly to mature myofibrils in cultured cardiac and skeletal muscle cells, supporting a three-step model of assembly in which some of the proteins in nascent myofibrils are proteolyzed to allow the assembly of mature myofibrils. Application of UPS inhibitors on cultured muscle cells suggests possible explanations for the off-target cardiac and skeletal muscle adverse effects of UPS drugs, which are used on cancer patients.
View Article and Find Full Text PDFWe present the draft genome of the bacterium strain AK152, a thermophilic, endospore-spore-forming, anaerobe isolated from a hot spring in Grensdalur, in Southwestern Iceland. This assembled genome will lay the foundation for identifying the carboxylic and amino acid fermentation pathways, suggesting biotechnological applications for this strain.
View Article and Find Full Text PDFIntroduction: The full assessment of bilingual children often involves at least one language for which formal vocabulary tests are lacking and which the examiner does not speak. We examined, in a sample of children with typical development (TD), whether a semantic verbal fluency task, typically used in research as a measure of executive function, could be used in the place of a formal vocabulary test to estimate vocabulary knowledge when formal tests are not available.
Method: 113 TD monolingual French speakers and TD bilinguals and with varying degrees of exposure to French, age 6 to 17 years, completed tests of vocabulary knowledge and semantic verbal fluency.
Article Synopsis
- The study investigates the use of optic nerve ultrasound to measure optic nerve sheath diameter (ONSD) as a potential diagnostic tool for giant cell arteritis (GCA).
- Patients with GCA showed significantly larger ONSD compared to those without the condition, suggesting that ultrasound could serve as a quick bedside test for GCA diagnosis.
- Further research with larger sample sizes is needed to confirm these results and explore if ONSD could act as a biomarker for GCA disease activity.