Pierre Fauchard (1678-1761): Pioneering Dental Surgeon of the Enlightenment Age.

Pierre Fauchard, widely referred to as the "Father of Modern Dentistry," fundamentally transformed the field with his seminal 1728 publication,  Born circa 1677 in Brittany, France, Fauchard's early exposure to severe dental conditions during his naval service catalyzed his pursuit of advancements in dental science. Upon transitioning from naval service to establish a practice in Angers, and subsequently gaining acclaim in Paris, Fauchard systematically documented and organized dental practices, encompassing oral surgery, orthodontics, periodontics, and prosthodontics, thereby laying the foundational framework for contemporary dental practices. Fauchard's innovations included the use of materials such as lead, tin, and gold for dental fillings and the introduction of early orthodontic techniques, notably the  His treatise also emphasized the importance of preventive care and oral hygiene, which provided a basis for modern dental hygiene protocols.

Effects of melatonin against experimentally induced apical periodontitis in rats.

Apical periodontitis is an inflammatory condition resulting from microbial invasion in the root canal system, causing periapical tissue destruction and bone resorption. This study investigated melatonin's effects, known for its antioxidant and anti-inflammatory properties, on experimentally induced apical periodontitis in rats. Three groups of rats were studied: control, apical periodontitis and apical periodontitis with melatonin treatment.

The Impact of Laser-Activated and Conventional Irrigation Techniques on Sealer Penetration into Dentinal Tubules.

The present study was aimed at comparing the efficacy of 1-hydroxyethylidene-1, 1-diphosphonic acid (HEDP) and ethylenediaminetetraacetic acid (EDTA) by using various final irrigation techniques on penetration of sealer. Traditional irrigation of root canals with a syringe limits the ability of sealer penetration. Various irrigants and activation techniques, including sonic and ultrasonic devices and various kinds of lasers, have been introduced to improve penetration of sealers into dentinal tubules.

Receptivity, autophagy, and implantation in endometriosis; does antioxidant work? An experimental study.

Implantation is a key point in pathological processes associated with infertility, especially in endometriosis. In this complex process, there is limited evidence to demonstrate the role of receptivity and autophagy. The present study aimed to evaluate LC3A/B, P62/SQSTM1, Beclin 1, and integrin expressions and receptivity and autophagy processes in endometriosis in pregnant rats with healthy endometriosis on day 6 of the process.