Eliminating malaria transmission requires targeting immature and mature gametocytes through lipoidal uptake of antimalarials.

Novel antimalarial compounds targeting both the pathogenic and transmissible stages of the human malaria parasite, Plasmodium falciparum, would greatly benefit malaria elimination strategies. However, most compounds affecting asexual blood stage parasites show severely reduced activity against gametocytes. The impact of this activity loss on a compound's transmission-blocking activity is unclear.

Can the Kohn-Sham gap be larger than the fundamental gap?

It is often stated that the exact Kohn-Sham HOMO-LUMO gap underestimates the fundamental gap. Here, using the Hubbard dimer as a model Hamiltonian, we show numerically that the exact Kohn-Sham gap can be larger than the fundamental gap.

Running Shoes of the Postmodern Footwear Era: A Narrative Overview of Advanced Footwear Technology.

The modern era of running shoes began in the 1960s with the introduction of simple polymer midsole foams, and it ended in the late 2010s with the introduction of advanced footwear technology (AFT). AFT is characterized by highly compliant, resilient, and lightweight foams with embedded, rigid, longitudinal architecture. This footwear complex improves a runner's efficiency, and it introduced a step change in running performance.

Field deployment of -infected using uncrewed aerial vehicle.

Over the past 50 years, there has been a marked increase in diseases like dengue fever, chikungunya, and Zika. The World Mosquito Program (WMP) has developed an approach that, instead of attempting to eliminate vector species, introduces into native populations through the release of -infected mosquitoes. Using this approach, a randomized controlled study recently demonstrated a 77% reduction in dengue across a treatment area within Yogyakarta, Indonesia.