Publications by authors named "D Jegadeesh Kumar"

The disposal of municipal solid waste (MSW) in urban areas is a big issue nowadays in most of the countries. Developing countries like India are struggling with the continuous indiscriminate disposal of MSW due to rapid increase in the urbanization, industrialization, and human population growth. The mismanagement of MSW causes adverse environmental impacts, public health risks, and other socio-economic problems.

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N-nitrosamine impurities have been detected in a vast variety of drug substances and drug products, showing concern for regulatory aspects. To meet the regulatory requirement for the concerned impurity, a sensitive analytical method capable of quantifying these impurities at a lower level with accuracy and precision is required. This article focuses on the development and validation of an analytical method for the simultaneous detection of nine nitrosamine impurities in a single method for nebivolol drug product using liquid chromatography-mass spectrometry/mass spectrometry-atmospheric pressure chemical ionization (LC-MS/MS-APCI).

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Introduction: Cardioplegia (CP) is integral to myocardial protection during cardiac surgery. Two standard cardioplegic solutions viz. Del Nido solution (DNS) and St Thomas solution (STS) are widely used in cardiac surgeries.

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Large iris defects are challenging to close due to shortage of tissue and opposite vector force. By using two pupilloplasty methods, we can close large iris defects with less tractional force or tethering. The trifold technique is a combination of trocar-assisted iris repair and single-pass four-throw (SFT) pupilloplasty for non-appositional large iris defects.

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Introduction: The development of a child is a crucial factor that ultimately affects the quality of life of children. Developmental delay can be prevented if it is identified early and adequate attention is given from the start.

Methodology: A cross-sectional analytical study was conducted between December and November 2022 on 450 children by multistage cluster sampling in the Ormanjhi block of Ranchi, Jharkhand.

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