Stakeholder prioritization preferences for individuals awaiting hip and knee arthroplasty.

Aims: Prolonged waits for hip and knee arthroplasty have raised questions about the equity of current approaches to waiting list prioritization for those awaiting surgery. We therefore set out to understand key stakeholder (patient and surgeon) preferences for the prioritization of patients awaiting such surgery, in order to guide future waiting list redesign.

Methods: A combined qualitative/quantitative approach was used.

The sexual and reproductive health needs and preferences of youths in sub-Saharan Africa: A meta-synthesis.

The sexual and reproductive health (SRH) needs of youths in sub-Saharan Africa are not being fully met, as evidenced by high rates of unintended pregnancies and sexually transmitted infections in this population. Understanding service needs and preferences of sub-Saharan African youths aged 10-24 years is critical for improving access and SRH outcomes and the focus of this systematic review of qualitative research. Four databases were searched with key words to identify relevant studies, supplemented by citation search, with an update in June 2023.

miRNA changes associated with differentiation of human embryonic stem cells into human retinal ganglion cells.

miRNA, short non-coding RNA, are rapidly emerging as important regulators in cell homeostasis, as well as potential players in cellular degeneration. The latter has led to interest in them as both biomarkers and as potential therapeutics. Retinal ganglion cells (RGC), whose axons connect the eye to the brain, are central nervous system cells of great interest, yet their study is largely restricted to animals due to the difficulty in obtaining healthy human RGC.

Biopsychosocial correlates of body satisfaction in 7- to 8-year old children: a cross-sectional and prospective investigation.

Background: Biopsychosocial factors have been associated with body satisfaction/dissatisfaction and related body image concerns in adolescence; however, few studies have investigated these relationships in middle childhood, an important developmental phase for body satisfaction. This study investigated relationships between a range of biological (body mass index), psychological (child anxiety/depression, self-esteem, and self-oriented and socially prescribed perfectionism) and sociocultural (mother's body dissatisfaction and comments about child's appearance, father's body dissatisfaction and comments about child's appearance, peer teasing and child's media exposure) factors and body satisfaction cross-sectionally and longitudinally in a sample of 7- and 8-year-old children.

Methods: In this study, participants from the longitudinal Children's Body Image Development Study (in which children had been followed-up annually from 3 years old) were assessed by interview at 7 years old (Time 1; n = 293: girls = 167, boys = 126) and 8 years old (Time 2; n = 222; girls = 126, boys = 96) and their parents completed a questionnaire at each time point.

Hindlimb locomotor biomechanics of the derived therizinosaur Nothronychus: Functional changes in the line to birds and convergence with large-bodied neornitheans.

Nothronychus graffami was a large therizinosaur represented by a single well-preserved individual from the Turonian Tropic Shale of southern Utah. It is characterized by an enlarged abdomen, small tail, and an extensively pneumatized axial skeleton, and is frequently regarded as herbivorous. Given the overall tail reduction and the development of a wide fused synsacrum with widely spaced acetabulae, it is reconstructed with an anteriorly rotated femur and a displaced resting ground reaction force anterior to the center of mass.