Publications by authors named "D J-H Lyu"
Restless legs syndrome (RLS) is a common sensorimotor sleep disorder that affects sleep quality of life. Much effort has been made to make progress in RLS pharmacotherapy; however, patients with RLS still report poor long-term symptom control. Comprehensive Mendelian randomization (MR) was performed to search for potential causal genes and drug targets using the cis-pQTL and RLS GWAS data.
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- Low-temperature stress is a major challenge for apple production, and galactinol acts as a key cryoprotectant.
- Exogenous application of galactinol on apple saplings was shown to reduce damage from cold stress, and transgenic plants overexpressing the MdGolS5 gene exhibited increased cold tolerance.
- The study highlights the potential of galactinol and its biosynthetic pathway in enhancing cold resistance in apples, providing insights for future genetic improvements.
Article Synopsis
- The research examined optimism bias during two key phases of COVID-19 in China, finding that people showed an initial optimism bias in February 2020, influenced by rising case numbers.
- In December 2022, during the Omicron outbreak, optimism bias remained but was less pronounced, showing that social connections' infection rates negatively impacted optimism while severity perception increased it.
- Overall, the study suggests that optimism bias could have positive effects by reducing anxiety and encouraging protective behaviors during the pandemic.
Purpose: Renal cell carcinoma (RCC), exhibiting remarkable heterogeneity, can be highly infiltrated by regulatory T cells (Tregs). However, the relationship between Treg and the heterogeneity of RCC remains to be explored.
Methods: We acquired single-cell RNA-seq profiles and 537 bulk RNA-seq profiles of TCGA-KIRC cohort.
The Impact of a New Case-Based Payment System on Quality of Care: A Difference-in-Differences Analysis in China.
Risk Manag Healthc Policy
December 2024
Purpose: China has developed and widely piloted a new case-based payment, ie, the "Diagnosis-Intervention Packet" (DIP) payment, which has a granular classification system. We evaluated the impact of DIP payment on the quality of care in a large pilot city in China and explored potential mechanisms of quality change.
Methods: The city started to implement DIP payment with a hospital-level cap on July 1, 2019.