Publications by authors named "D J Warner"
The embryonic environment is critical for the development of many ectothermic vertebrates, which makes them highly vulnerable to environmental change. Changes in temperature and moisture, in particular, are known to influence embryo survival and offspring phenotypes. While most papers concerning phenotypic development of terrestrial ectotherms focus on the role of temperature on eggs and embryos, the comparatively small number of studies on the effects of substrate moisture are well suited for quantitative analysis aimed at guiding future research.
View Article and Find Full Text PDFImpact of chronic ethanol consumption and SARS-COV-2 on the liver and intestine: A pilot dose-response study in mice.
Alcohol Clin Exp Res (Hoboken)
January 2025
Background: During the coronavirus disease 2019 (COVID-19) pandemic, there was a marked increase in alcohol consumption. COVID-19 superimposed on underlying liver disease notably worsens the outcome of many forms of liver injury. The goal of a current pilot study was to test the dual exposure of alcohol and COVID-19 infection in an experimental animal model of alcohol-associated liver disease (ALD).
View Article and Find Full Text PDFThe mycobacterial mutasome - comprising ImuA', ImuB, and DnaE2 - has been implicated in DNA damage-induced mutagenesis in Mycobacterium tuberculosis. ImuB, which is predicted to enable mutasome function via its interaction with the β clamp, is a catalytically inactive Y-family DNA polymerase. Like some other members of the Y-family, ImuB features a recently identified amino acid motif with homology to the RecA N-terminus (RecA-NT).
View Article and Find Full Text PDFFactors underlying the association between , subspecies infection and colorectal cancer: a mini review.
Gut Microbiome (Camb)
November 2024
Article Synopsis
- Sgg is a gram-positive bacterium linked to infective endocarditis and colorectal cancer (CRC), thriving in the colorectal tumor environment.
- It has specialized features like pili for cell adhesion, bile salt hydrolase, and gallocin that help it grow in the bile-rich conditions typical of colorectal tumors.
- Sgg also affects oncogenic pathways, particularly the Wnt/β-catenin signaling, and promotes CRC progression by utilizing tumor metabolites and inducing harmful biotransformation in cancer cells.
Background/objectives: Dry eye disease (DED) is an exceedingly common diagnosis in patients, yet recent analyses have demonstrated patient education materials (PEMs) on DED to be of low quality and readability. Our study evaluated the utility and performance of three large language models (LLMs) in enhancing and generating new patient education materials (PEMs) on dry eye disease (DED).
Subjects/methods: We evaluated PEMs generated by ChatGPT-3.