Publications by authors named "D J Shearman"

Arbovirus surveillance of wild-caught mosquitoes is an affordable and sensitive means of monitoring virus transmission dynamics at various spatial-temporal scales, and emergence and re-emergence during epidemic and interepidemic periods. A variety of molecular diagnostics for arbovirus screening of mosquitoes (known as xeno-monitoring) are available, but most provide limited information about virus diversity. Polymerase chain reaction (PCR)-based screening coupled with RNA sequencing is an increasingly affordable and sensitive pipeline for integrating complete viral genome sequencing into surveillance programs.

View Article and Find Full Text PDF
Article Synopsis
  • Surveillance of zoonotic pathogens in animals is crucial for understanding how diseases spread, but traditional methods can be expensive and technically challenging.
  • By using blood-fed mosquitoes as samples, researchers can analyze a variety of vertebrate species and their exposure to pathogens, like the Ross River virus (RRV).
  • In a study conducted in Brisbane, they found a high prevalence of RRV exposure in both humans (52%) and cattle (70%), demonstrating the effectiveness of this non-invasive method to monitor disease risks in wildlife populations.
View Article and Find Full Text PDF

The KidGen Collaborative's Policy Implementation Workshop 2023 celebrated the 10th anniversary of Australia's first kidney genetics clinic in Brisbane. This event marked the establishment of a national network now comprising 19 kidney genetics clinics across Australia, all dedicated to providing equitable access to genomic testing for families affected by genetic kidney diseases. The workshop reflected on past progress and outlined future objectives for kidney genetics in Australia, recognising the collaborative efforts of clinical teams, researchers, and patients.

View Article and Find Full Text PDF

Tephritid fruit flies are amongst the most devastating pests of horticulture, and Sterile Insect Technique (SIT) programs have been developed for their control. Their interactions with viruses are still mostly unexplored, yet, viruses may negatively affect tephritid health and performance in SIT programs, and, conversely, constitute potential biological control agents. Here we analysed ten transcriptome libraries obtained from laboratory populations of nine tephritid species from Australia (six species of Bactrocera, and Zeugodacus cucumis), Asia (Bactrocera dorsalis) and Europe (Ceratitis capitata).

View Article and Find Full Text PDF