Cytogenetic investigation of occupational exposure to epichlorohydrin.

Cytogenetic evaluation of peripheral lymphocytes from 93 workers currently exposed to epichlorohydrin has revealed an increase in aberration rates as compared to that of a 75-person group seen for preemployment examination. Statistically significant differences were found in the distribution of individuals with chromatid breaks, chromosome breaks, severely damaged cells, and total abnormal cells. These results confirm the observations of Kucerova et al.

Dominant lethality in frog embryos after paternal treatment with triethylenemelamine: cytogenetics, morphology, and swimming capability.

Male frogs (Rana pipiens) were injected intraperitoneally with triethylenemelamine (TEM). The injected males were held for seven days to permit TEM interaction with sperm. The TEM-treated males were then spermiated with human chorionic gonadotropin (HCG) and the ova of normal females were inseminated with the sperm.