Publications by authors named "D J Pandya"
PM is the most hazardous air pollutant due to its smaller size, which allows deeper bodily penetration. Three diverse regions from Gujarat, India, namely Sector 10, Maninagar, and Vatva, which have green space, high population concentration, and industries, respectively, were chosen to forecast PM concentration for the next day. Four statistical models, including Multiple Linear Regression (MLR), Principal Component Regression (PCR), Simple Exponential Smoothing (SES), and Autoregressive Integrated Moving Average (ARIMA), were chosen to forecast PM levels.
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- * A six-month cross-sectional study was conducted to assess tobacco habits and oral potentially malignant disorders (OPMDs) among patients, focusing on consumption patterns, reasons for use, and age groups.
- * Findings revealed higher tobacco use in males, particularly chewing tobacco; OPMDs like tobacco pouch keratosis and leukoplakia were prevalent, with stress often cited as a key factor in tobacco consumption.
Fibroblast activation protein alpha (FAP) is a serine protease that is expressed at basal levels in benign tissues but is overexpressed in a variety of pathologies, including cancer. Despite this unique expression profile, designing effective diagnostic and therapeutic agents that effectively target this biomarker remain elusive. Here we report the structural characterization of the interaction between a novel single domain antibody (sdAbs), I3, and FAP using cryo-electron microscopy.
View Article and Find Full Text PDFPathologic response is an endpoint in many ongoing clinical trials for neoadjuvant regimens, including immune checkpoint blockade and chemotherapy. Whole-slide scanning of glass slides generates high-resolution digital images and allows for remote review and potential measurement with image analysis tools, but concordance of pathologic response assessment on digital scans compared with that on glass slides has yet to be evaluated. Such a validation goes beyond previous concordance studies, which focused on establishing surgical pathology diagnoses, as it requires quantitative assessment of tumor, necrosis, and regression.
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- The study looked at whether a medical procedure called thrombectomy helps patients who have a large stroke as seen on a specific type of scan called a noncontrast CT within 24 hours of having the stroke.
- It involved 300 patients from different hospitals who were split into two groups; one group received the thrombectomy treatment, while the other only received regular care.
- The main goal was to see if those who had thrombectomy had better recovery after 90 days compared to those who didn’t, along with checking if there were any serious side effects.