Publications by authors named "D J Ortola"
Background: The available evidence on pseudo-patella baja (PPB) is limited. The purpose of this study is to investigate prospectively the occurrence of PPB after primary total knee arthroplasty and its clinical consequences in a large series of patients with a minimum follow-up of 2 years. PPB was defined as a patella distally displaced in relationship to the femoral trochlea with absence of patellar tendon shortening (Grelsamer RP.
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- This study aimed to compare pre-made antibiotic-loaded spacers with two commercial antibiotic agents and custom-made cements with three added antibiotics, focusing on effectiveness, infection control, complications, and patient satisfaction.
- A cohort of 112 patients was analyzed, divided equally between those receiving a pre-formed cement spacer with two antibiotics and a spacer loaded with three antibiotics, with a follow-up period averaging 32.87 months.
- Findings indicated a low infection recurrence rate of 2.70% and suggested that using spacers loaded with three antibiotics is beneficial for patients at risk of multi-resistant infections, potentially reducing the need for further surgical interventions.
Quantitative study on Vancomycin release from cement in 3 different formulations: preliminary results and antimicrobial activity.
J Biol Regul Homeost Agents
November 2018
The purpose of this study is to investigate the best preparation method of the cement powder mixture, solvent and antibiotic in order to obtain the greatest amount of antibiotic in the joint for the longest time as possible. At time T0 the three samples, packed in a sterile environment in different formulations, were placed in sterile tubes, adding to each one 5 ml of saline phosphate buffer solution (PBS) and put in a stove at 37°C for 24 h. A sample of PBS without cement (T control) was also created.
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