Publications by authors named "D J Newport"
Article Synopsis
- - This study explored how trauma exposure, post-traumatic stress disorder (PTSD), and perceived social support relate to each other among a diverse group of 1,829 children and adolescents aged 8-21 who have experienced trauma.
- - It found that higher trauma burden resulted in lower perceived social support from family and peers, especially for those with interpersonal trauma, but this effect was more pronounced in youth without a PTSD diagnosis.
- - The research also revealed that being assigned female at birth correlated with more perceived support from family but less from close friends, emphasizing the complex dynamics between trauma, mental health, and social relationships.
The pathological signature of Alzheimer's disease (AD) includes the accumulation of toxic protein aggregates, mainly consisting of amyloid beta (Aβ). Recent strides in fundamental research underscore the pivotal role of waste clearance mechanisms in the brain suggesting it may be an early indication of early onset AD. This study delves into the involvement of leptomeningeal cells (LMCs), crucial components forming integral barriers within the clearance system, in the context of AD.
View Article and Find Full Text PDFComorbidity between post-traumatic stress disorder (PTSD) and substance use disorder may be explained by a prospective trauma risk conferred by both conditions. The current study modeled concurrent and prospective associations of trauma, PTSD symptoms, and substance use (SU) behavior among trauma exposed youth (ages 8-20). Clinical interviews assessed trauma exposure, PTSD symptom severity, and SU behavior at baseline and at six- and 12-month follow up study visits (N = 2,069).
View Article and Find Full Text PDFUnlabelled: History of childhood maltreatment (CM) is common and robustly associated with prenatal and postpartum (perinatal) depression. Given perinatal depression symptom heterogeneity, a transdiagnostic approach to measurement could enhance understanding of patterns between CM and perinatal depression.
Methods: In two independently collected samples of women receiving care at perinatal psychiatry clinics (n = 523 and n = 134), we categorized longitudinal symptoms of perinatal depression, anxiety, stress, and sleep into transdiagnostic factors derived from the Research Domain Criteria and depression literatures.
Divergent conceptualization of posttraumatic stress disorder (PTSD) within the Diagnostic and Statistical Manual of Mental Disorders (5th ed.; DSM-5) and International Statistical Classification of Diseases and Related Health Problems (11th ed..
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