Publications by authors named "D J Maurer"
Background And Aims: Endothelial dysfunction predicts elevated cardiovascular (CV) risk in healthy individuals. Aerobic exercise reduces endothelial dysfunction in part by improving CV risk factors. Yet, this explains less than 50 % of the effect and a direct influence of exercise training on the endothelium is discussed as possible contributor.
View Article and Find Full Text PDFArticle Synopsis
- Researchers isolated various monoclonal antibodies (mAbs) from human B cells that target the hemagglutinin (HA) protein of influenza, focusing on both H1 and H3 subtypes.
- The study improved the effectiveness of H1 mAbs against contemporary strains and identified potential viral escape routes using deep mutational scanning.
- For H3 mAbs, advanced imaging techniques mapped specific epitopes, showing how these antibodies might guide the development of next-generation vaccines that can provide broader protection against influenza.
Article Synopsis
- Perioperative care demands skilled health professionals, and Advanced Practice Nurses (APN) in Anesthesia can enhance this care through expanded competencies and roles.
- A scoping review analyzed literature from the last decade to clarify the scope of practice (SOP) and prerequisites for APN Anesthesia, revealing a lack of standardization across countries.
- The review highlighted the certified registered nurse anesthetist in the U.S. as the most developed role, emphasizing their autonomy and diverse practice settings, including postoperative care and specialized medical conditions.
Bats harbor viruses that can cause severe disease and death in humans including filoviruses (e.g., Ebola virus), henipaviruses (e.
View Article and Find Full Text PDFArticle Synopsis
- A retrospective study was conducted on 319 adults with early-stage non-small cell lung cancer (NSCLC) in Austria from January 2018 to December 2021, focusing on their profiles and initial treatment options.
- Key findings showed that biomarkers like PD-L1, KRAS, and EGFR were tested, with varying treatment paths for patients in different stages (StI: 82% underwent surgery, StII: 85%, StIII: 36%).
- The study highlighted that treatments were generally in line with existing guidelines, occurring before the introduction of immune checkpoint inhibitors and targeted therapies in earlier treatment stages.