Exploring body image among transgender and nonbinary adults: Considering positive body image and the pursuit of gender-affirming surgery.

This study explored body image among transgender and nonbinary adults, including their body appreciation, embodiment, general psychological distress, and gender identity-related pride. This study also considered participants' pursuit of gender-affirming surgery and mental health services. This cross-sectional survey examined participants' ( = 214;  = 28.

Irreversible Electroporation and β-Glucan Induced Trained Innate Immunity for the Treatment of Pancreatic Ductal Adenocarcinoma: A Phase II Study.

Introduction: Irreversible electroporation(IRE) has augmented the effects of certain immunotherapies in pancreatic cancer(PDA). Yeast-derived particulate beta-glucan induces trained innate immunity and has successfully reduces murine PC tumor burden. This is a Phase II study to test the hypothesis that IRE may augment beta-glucan induced trained immunity in patients with PDA.

Mechanisms of chromatin remodeling by an Snf2-type ATPase.

Chromatin remodeling enzymes play a crucial role in the organization of chromatin, enabling both stability and plasticity of genome regulation. These enzymes use a Snf2-type ATPase motor to move nucleosomes, but how they translocate DNA around the histone octamer is unclear. Here we use cryo-EM to visualize the continuous motion of nucleosomal DNA induced by human chromatin remodeler SNF2H, an ISWI family member.

Management Outcomes after Image-guided Percutaneous Biopsy for Suspected Vertebral Osteomyelitis-Discitis.

Background And Purpose: Studies show a modest yield for image-guided biopsy of suspected vertebral osteomyelitis-discitis. Many studies evaluate factors to improve diagnostic yield, and few studies assess how biopsy results impact clinical management. We aim to evaluate the impact of biopsy results on clinical management in suspected vertebral osteomyelitis-discitis.

A New Synthetic Analogue Of The Burckhardtite Mineral, PbTeGa[AlSiO]O: Synthesis, Structure, And Properties.

The mineral, Burckhardtite, PbTeFe[AlSiO]O, is synthesized and characterized. A new analogue, PbTeGa[AlSiO]O, is successfully prepared for the first time under laboratory conditions. The substitution of Ga by TiM (M=Co, Ni) results in new compounds with the Burckhardtite mineral structure.