Publications by authors named "D J Livorsi"
A pilot intervention trial to reduce the use of post-procedural antimicrobials after common endourologic surgeries.
Infect Control Hosp Epidemiol
November 2024
Objective: Post-procedural antimicrobial prophylaxis is not recommended by professional guidelines but is commonly prescribed. We sought to reduce use of post-procedural antimicrobials after common endoscopic urologic procedures.
Design: A before-after, quasi-experimental trial with a baseline (July 2020-June 2022), an implementation (July 2022), and an intervention period (August 2022-July 2023).
Adaptation and validation of an antibiotic prescribing, peer comparison metric for respiratory tract diagnoses in walk-in clinics: a mixed-methods analysis.
Antimicrob Steward Healthc Epidemiol
October 2024
Article Synopsis
- - The study examines antibiotic overuse in walk-in clinics, focusing on the effectiveness of a specific metric that tracks antibiotic prescribing for respiratory tract diagnoses (RTDs) while excluding complicating factors.
- - Data from 331,496 clinic visits between 2018-2022 revealed that 36.5% met RTD criteria, with 36.7% of those receiving antibiotics; factors like patient age and comorbidities influenced prescribing rates.
- - Provider interviews indicated that the RTD metric is acceptable for assessing antibiotic prescribing practices, suggesting it has validity, but further research is needed to evaluate its effectiveness as a feedback tool.
Article Synopsis
- - The study focuses on exploring deep-sea invertebrates in Ireland, specifically looking at bubble gum coral collected from a depth of 1500 m in Whittard Canyon, to discover new marine metabolites with potential medical applications.
- - Researchers isolated three new diterpenes (miolenol, epoxymiolenol, and epoxycoraxeniolide A) and identified their structures using NMR analysis and advanced techniques.
- - After testing the eight isolated compounds for cytotoxicity and antimalarial activity, none exhibited significant bioactivity, indicating the need for further exploration of deep-sea diversity.
Improving shared decision-making around antimicrobial-prescribing during the end-of-life period: a qualitative study of Veterans, their support caregivers and their providers.
Antimicrob Steward Healthc Epidemiol
May 2024
Article Synopsis
- Antimicrobials are medicines used during end-of-life care to help patients feel better, but they can cause problems like making infections harder to treat.
- Doctors, patients, and caregivers believe it's important to talk about these medicines together to make the best decision for the patient's care.
- Some issues like not having enough time to talk and uncertainty about how long a patient has left can make these conversations harder, but good communication can help everyone agree on a care plan.
Five steps to high quality antimicrobial stewardship research.
Antimicrob Steward Healthc Epidemiol
May 2024
The escalating threat of antimicrobial resistance (AMR) necessitates impactful, reproducible, and scalable antimicrobial stewardship strategies. This review addresses the critical need to enhance the quality of antimicrobial stewardship intervention research. We propose five considerations for authors planning and evaluating antimicrobial stewardship initiatives.
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