Publications by authors named "D J Herzig"

Background: Post bariatric hypoglycaemic (PBH) is a late complication of weight loss surgery, characterised by critically low blood glucose levels following meal-induced glycaemic excursions. The disabling consequences of PBH underline the need for the development of a decision support system (DSS) that can warn individuals about upcoming PBH events, thus enabling preventive actions to avoid impending episodes. In view of this, we developed various algorithms based on linear and deep learning models to forecast PBH episodes in the short-term.

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Aims: Current evidence of the impact of acute exercise on insulin levels in individuals with type 1 diabetes remains controversial. Therefore, we conducted a systematic review and meta-analysis to explore exercise-induced changes in insulin levels.

Materials And Methods: We conducted a systematic review (until 05 November 2023) and meta-analysis exploring the effect of exercise on insulin concentration in individuals with type 1 diabetes.

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Aims/hypothesis: The majority of hybrid closed-loop systems still require carbohydrate counting (CC) but the evidence for its justification remains limited. Here, we evaluated glucose control with simplified meal announcement (SMA) vs CC in youth and young adults with type 1 diabetes using the mylife CamAPS FX system.

Methods: We conducted a two-centre, randomised crossover, non-inferiority trial in two University Hospitals in Switzerland in 46 participants (aged 12-20 years) with type 1 diabetes using multiple daily injections (n=35), sensor-augmented pump (n=4) or hybrid closed-loop (n=7) therapy before enrolment.

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Article Synopsis
  • Roux-en-Y gastric bypass (RYGB) surgery can cause post-bariatric hypoglycaemia (PBH) due to changes in glucose handling by the liver.
  • A study compared RYGB patients with PBH to healthy controls by tracking glucose and hormone levels after consuming glucose, using advanced imaging techniques.
  • Results showed that RYGB patients had distinct glucose and insulin responses, including a quicker rise and fall in glucose levels and lower sensitivity to insulin, but did not have impaired liver glucose uptake or output contributing to PBH.
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Article Synopsis
  • The study introduces a new rib-sparing technique for thoracic corpectomy, which minimizes post-operative complications associated with rib removal during spinal surgery.
  • Researchers conducted a chart review of 36 corpectomies performed on 32 patients from 2015 to 2023, noting key metrics like estimated blood loss and operative time.
  • Results showed the technique was effective, with an average post-operative stay of 6.5 days, highlighting the advantages of using an ultrasonic bone scalpel for this procedure.
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