Risk Factors for Rescue Therapy in Crohn's Patients Maintained on Infliximab After Withdrawal of the Immunomodulator: A Long-Term Follow-Up.

Background: Usefulness of thiopurine and scheduled infliximab combination therapy in non-immunomodulator (IM)-naïve Crohn's disease (CD) patients and the optimal length of dual therapy are still debated.

Aims: To determine proportion of patients developing disease flare requiring rescue therapy and risk factors associated with disease flare after de-escalation of IM from combination therapy.

Methods: Adult CD patients in clinical remission on combination therapy were identified from a large single-center database between 2002 and 2009.

Comparing diagnostic yield of a novel pan-enteric video capsule endoscope with ileocolonoscopy in patients with active Crohn's disease: a feasibility study.

Background And Aims: Crohn's disease (CD) is typically diagnosed with ileocolonoscopy (IC); however, when inflammation is localized solely in the small bowel, visualization of the entire small-bowel mucosa can be challenging. The aim of this study was to compare the diagnostic yield of a pan-enteric video capsule endoscope (small-bowel colon [SBC] capsule) versus IC in patients with active CD.

Methods: This was a prospective, multicenter study.

Narrow-band imaging versus white light for the detection of proximal colon serrated lesions: a randomized, controlled trial.

Background: The value of narrow-band imaging (NBI) for detecting serrated lesions is unknown.

Objective: To assess NBI for the detection of proximal colon serrated lesions.

Design: Randomized, controlled trial.

Incidence and risk factors for lymphoma in a single-center inflammatory bowel disease population.

Aims: Previous studies on the risk of lymphoma in inflammatory bowel disease (IBD) have yielded conflicting results. We aim to determine the incidence and risk factors for lymphoma in a large IBD population.

Methods: Patients with lymphoma were identified from a single-center IBD database.