Contrast injection around mandril wire of an Accustick system using an extension tubing: technical note.

We describe a technique for injecting contrast material around a mandril wire of an Accustick access system through the outer 6 French sheath of this system, thus identifying the position of the wire. This is accomplished by using an extension tubing.

Exaggerated renal vasodilator response to calcium entry blockade in first-degree relatives of essential hypertensive subjects.

Because an inherited renal factor may contribute to essential hypertension in humans, the study of family members is attractive. To assess the determinants of renal vascular tone, graded doses of either diltiazem (10-1000 micrograms/min) or acetylcholine (1-100 micrograms/min) were infused into the renal artery in 52 normotensive subjects, 16 with and 36 without a family history of hypertension when they were in balance on either a 10-mEq or 200-mEq sodium intake. Renal blood flow was measured with 133Xe.