Publications by authors named "D J Fedele"

Objective: Parent-child communication is integral to pediatric asthma management. This review evaluates parent-child communication among youth with asthma and their caregivers. It aims to characterize the type of communication according to a unifying framework (Murphy, L.

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Article Synopsis
  • The study investigates myocardial infarction with non-obstructive coronary arteries (MINOCA), revealing that its underlying causes are diverse and not well understood in clinical settings.
  • A review of 45 studies found that 53% of patients with MINOCA had non-obstructive coronary artery stenosis, with significant findings from optical coherence tomography and vasomotor tests.
  • Patients with non-obstructive coronary arteries showed a higher risk of death or myocardial infarction at one year compared to those with normal arteries, indicating the need for better diagnostic methods in understanding MINOCA.
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Background: This report summarizes the 2023 inaugural annual meeting of the Cystic Fibrosis Foundation's Prioritizing Research in Mental Health (PRIME) working group. This workshop focused on mental health and elexacaftor/tezacaftor/ivacaftor (ETI).

Methods: We reviewed existing literature and identified key gaps and study design considerations in preclinical work, pharmacokinetics/pharmacodynamics, mood/anxiety, quality of life/self-perception, neuropsychological symptoms, sleep, and symptom management.

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Takotsubo syndrome (TTS) is a clinical syndrome characterized by a transient left ventricular dysfunction whose diagnosis can be challenging due to its resemblance to acute myocardial infarction (AMI). Despite the growing recognition of TTS, acute complications and long-term mortality rates are comparable to those observed in AMI patients. In this context, a systematic diagnostic approach is imperative for an accurate patient assessment, with due consideration of the distinctive characteristics and optimal timing of each imaging modality.

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