Publications by authors named "D J Duncker"
[Left bundle branch (area) pacing: lead positioning and implant criteria-step for step].
Herzschrittmacherther Elektrophysiol
December 2024
Left bundle branch area pacing is currently the most common form of physiological pacing prior to His bundle pacing. It is intended to prevent or correct the development of pacemaker-induced cardiomyopathy and is being used more and more frequently. In order to be able to perform this successfully, knowledge regarding the specific anatomy and radiological anatomy as well as the ECG criteria for left bundle branch pacing is required in addition to knowledge of the tools.
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- Cardiac implantable electronic devices (CIEDs) can experience electromagnetic interference from various sources, including household and medical equipment, which can lead to malfunctions.
- A 79-year-old man experienced presyncope due to his abandoned abdominal pacemaker reactivating and interfering with his active leadless pacemaker, resulting in pacing problems and symptoms.
- The situation was managed by adjusting the active pacemaker's settings, but ultimately the best solution was to remove the abandoned pacemaker to prevent further complications.
Aims: Baroreceptor activation therapy (BAT) is a promising new treatment strategy for patients with heart failure with reduced ejection fraction (HFrEF). It provides symptomatic relief, improvement in left ventricular function and reduction of cardiac biomarkers. Data regarding the long-term effect of BAT on HFrEF are scarce.
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- The study explores the effectiveness of using a smartphone app to monitor the time patients spend experiencing atrial fibrillation (AF) and related symptoms after AF ablation.
- A total of 484 patients participated, showing high adherence and satisfaction with the app, which measured AF and symptom data three times daily.
- Results indicated strong correlations between AF and symptom recordings, with most patients showing a paroxysmal AF pattern, suggesting successful monitoring through the app could aid in evaluating patient outcomes post-ablation.
Article Synopsis
- - This study aimed to create a realistic 3D model of human atherosclerosis by coculturing different cell types, including smooth muscle cells and foam cells, to mimic a diseased blood vessel and study immune cell interactions under flow conditions.
- - Researchers developed a specialized coculture protocol using fluorescently labeled human cells and examined how these cells behaved in normal vs. atherosclerotic vessel environments over 24 hours of perfusion.
- - Results showed the model formed early atherosclerotic lesions, with distinct layers and foam cell accumulation, while circulating immune cells (THP-1 monocytes) exhibited movement into the vessel walls and responded to atherosclerosis-related signals.