Sevoflurane has no effect on sinoatrial node function or on normal atrioventricular and accessory pathway conduction in Wolff-Parkinson-White syndrome during alfentanil/midazolam anesthesia.

Background: The effects of sevoflurane on the electrophysiologic properties of the human heart are unknown. This study evaluated the effects of sevoflurane on the electrophysiologic properties of the normal atrioventricular conduction system, and on the accessory pathways in patients with Wolff-Parkinson-White syndrome, to determine its suitability as an anesthetic agent for patients undergoing ablative procedures.

Methods: Fifteen patients with Wolff-Parkinson-White syndrome undergoing elective radiofrequency catheter ablation were studied.

Monitoring of brainstem function during vertebral basilar aneurysm surgery. The use of spontaneous ventilation.

Monitoring of cardiovascular, respiratory, and evoked potential parameters has been advocated during posterior fossa surgery to detect brainstem ischemia that may result from surgical manipulations. We report here our retrospective and smaller prospective experience of spontaneous ventilation as a monitor in patients undergoing vascular surgical procedures in the posterior fossa. Forty patients' charts were reviewed retrospectively, and 10 patients were studied prospectively.