Publications by authors named "D J Crull"

Background Maximum oxygen uptake (VO₂max) is a predictor for postoperative complications after esophagectomy. Cardiopulmonary Exercise Test (CPET) is the golden standard for measuring VO₂max. The alternative Steep Ramp Test (SRT) is less strenuous with several benefits, providing an estimation of VO₂max.

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Esophageal cancer can be treated effectively with esophagectomy; however, the postoperative complication rate is high. In this paper, we study to what extent machine learning methods can predict anastomotic leakage and pneumonia up to two days in advance. We use a dataset with 417 patients who underwent esophagectomy between 2011 and 2021.

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Article Synopsis
  • This study investigated how different grades of tumor response (TRG) and a new scoring system (TRG-ypN) relate to cancer recurrence and survival in patients with esophageal adenocarcinoma after treatment.
  • The research, which included 2,746 patients treated between 2007 and 2016, found that lower TRG scores corresponded to lower recurrence rates and longer overall survival, with TRG1 patients having better outcomes than those with higher scores.
  • Additionally, residual nodal disease had a more significant negative impact on prognosis compared to remaining disease at the primary tumor site, highlighting the importance of nodal status in treatment outcomes.
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Background: Anastomotic leakage is one of the most life-threatening complications after Ivor Lewis esophagectomy (ILE), with various treatment strategies. Endoscopic techniques are emerging as a less invasive alternative to surgery. Among the current endoscopic techniques, a single placement of an endoluminal nasogastric tube inside the cavity with controlled suction drainage (SD) seems to be an attractive option.

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Objective: This study investigated the patterns, predictors, and survival of recurrent disease following esophageal cancer surgery.

Background: Survival of recurrent esophageal cancer is usually poor, with limited prospects of remission.

Methods: This nationwide cohort study included patients with distal esophageal and gastroesophageal junction adenocarcinoma and squamous cell carcinoma after curatively intended esophagectomy in 2007 to 2016 (follow-up until January 2020).

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