Publications by authors named "D J Chan"

Reciprocal neuronal connections exist between the internal organs of the body and the nervous system. These projections to and from the viscera play an essential role in maintaining and finetuning organ responses in order to sustain homeostasis and allostasis. Functional maps of brain regions participating in this bidirectional communication have been previously studied in awake humans and anesthetized rodents.

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Background: While healthy dietary and lifestyle factors have been individually linked to lower colorectal cancer (CRC) risks, recommendations for whole diet-lifestyle patterns remained unestablished due to limited studies and inconsistent pattern definitions.

Objective: This updated review synthesized literature on dietary-lifestyle patterns and CRC risk/mortality.

Methods: PubMed and Embase were searched through 31 March 2023 for randomized controlled trials and prospective cohort studies examining adulthood dietary patterns combined with modifiable lifestyle factors such as adiposity, smoking, alcohol consumption, physical activity, and/or others.

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Background: Hallux valgus (HV) is the most prevalent foot condition, associated with a decline in quality of life and a high rate of complications. Pedobarography can be a diagnostic tool, although controversies exist due to differences in measurement scales, type of capture, software, and hardware used. Deformity level differences have not been thoroughly explored.

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As expensive therapeutics rise to the fore of heart failure management, out-of-pocket (OOP) medication costs have become increasingly relevant to patient care. Prescription medication costs influence medical decision-making and affect adherence. Yet, individualized cost estimates are seldom available during clinical encounters when prescription decisions are made.

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Article Synopsis
  • Developed a 3-D acoustic radiation force impulse (ARFI) system for prostate imaging to identify cancerous regions and guide biopsies in one visit using a transrectal probe and 3-D visualization software.
  • The system was tested in a clinical trial comparing ARFI-guided targeted transperineal biopsies with other standard biopsy methods.
  • Results showed ARFI was less effective for lower-grade cancers but performed well for higher-grade cancers, suggesting it could enhance biopsy accuracy when combined with 2-D imaging techniques.
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