Publications by authors named "D J Bewick"

Article Synopsis
  • - Antiplatelet therapy (APT) is crucial for preventing atherothrombotic events in patients with cardiovascular disease, and effective strategies need to consider both risk of adverse events and bleeding.
  • - The updated Canadian guidelines provide recommendations on APT use for various conditions, including primary prevention, dual therapy duration post-PCI, and treatment of patients with acute coronary syndrome (ACS).
  • - These guidelines are based on systematic reviews and meta-analyses, ensuring evidence-based approaches for managing APT in different patient scenarios, including those requiring surgery or oral anticoagulation.
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Introduction: Dual antiplatelet therapy (DAPT) following percutaneous coronary intervention (PCI) reduces major adverse cardiovascular events (MACE) and stent thrombosis. However, DAPT duration is a concern in high bleeding risk (HBR) patients. We evaluated the effect of short DAPT (1-3 months) compared to standard DAPT (6-12 months) on bleeding and ischemic events in HBR PCI.

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Introduction: The sentinel lymph node (SLN) procedure for vulva cancer is a safe alternative to a radical inguino-femoral lymphadenectomy (IFLN) for small unifocal tumours. SLN evaluation through biopsy and ultra-staging has helped gynaecological oncology surgeons improve operative morbidity with no cost to oncologic safety. Established techniques for groin SLN detection and excision in vulvar cancer use Tc-nanocolloid radiotracer and blue dye (BD) for identification of the SLN.

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