A decision-space model explains context-specific decision-making.

Optimal decision-making requires consideration of internal and external contexts. Biased decision-making is a transdiagnostic symptom of neuropsychiatric disorders. We created a computational model demonstrating how the striosome compartment of the striatum constructs a context-dependent mathematical space for decision-making computations, and how the matrix compartment uses this space to define action value.

Brain health is essential for smooth economic transitions: towards socio-economic sustainability, productivity and well-being.

Optimal brain health is essential to smoothing major global skill-intensive economic transitions, such as the bioeconomy, green, care economy and digital transitions. Good brain health is vital to socio-economic sustainability, productivity and well-being. The care transition focuses on recognizing and investing in care services and care work as essential for economic growth and social well-being.

Epigenetic biomarker for preeclampsia-associated preterm birth and potential preventative medicine.

Preterm birth (PTB) has dramatically increased within the population (i.e. >10%) and preeclampsia is a significant sub-category of PTB.

Multimodal brain age indicators of internalising problems in early adolescence: A longitudinal investigation.

Background: Adolescence is a time of increased risk for the onset of internalising problems, particularly in females. However, how individual differences in brain maturation relate to the increased vulnerability for internalising problems in adolescence remains poorly understood due to a scarcity of longitudinal studies.

Methods: Using Adolescent Brain Cognitive Development (ABCD) Study data, we examined longitudinal associations between multimodal brain age and youth internalising problems.

Remembering Nightingale in her turbulent times: Introducing the Theory of Integral Nursing in our turbulent times.

Aim: To connect selected examples from Florence Nightingale's life with concerns for the distress nurses are experiencing worldwide.

Background: We live in turbulent times of disease, armed conflict, vast climate change, and social injustice-factors exacerbating illness and impacting health-factors Nightingale also addressed throughout her life.

Sources Of Evidence: The Theory of Integral Nursing (TIN) is introduced with related examples of nursing's problems and solutions seen through integral lenses at the individual, group, grassroots, and global levels.