Publications by authors named "D Iu Penionzhkevich"

The objective of the present study was to evaluate clinical efficiency of peloidotherapy in the early reconvalescence period following cerebral ischemic stroke. A rationale for the application of peloidotherapy is presented based on the results of follow-up of 60 patients (26 men and 34 women) aged from 43 to 70 years at the early stage of recovery (within 10 weeks and more after stroke). Special attention was given to clinical dynamics of the post-stroke condition and the influence of peloidotherapy on the mechanisms underlying formation of cerebral hemodynamic effects, adaptive changes in the functional systems of hemostasis and microcirculation, and development of pathophysiological cascade of metabolic processes in the brain.

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A purpose of the present research was the development of new treatment technologies for patients with cerebrovascular diseases by the complex application of medical physical factors directed to the correction of brain metabolism. An application of electrophoresis of mexidol and dimephosphon in the treatment of 80 patients with cerebrovascular diseases is substantiated. The clinical dynamics and effect of electrophoresis of mexidol and dimephosphon as a monotherapy as well as in combination with variable magnetic field and darsonvalization on mechanisms of electrophysiological processes, ways of formation of cerebral hemodynamic effects and adaptation in the functional systems of homeostasis and microcirculation and on the pathophysiological cascade of brain metabolism in single/serial applications were studied.

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This paper reports the development and application of a new physiotherapeutic modality for the treatment of patients with cerebrovascular diseases and shows for the first time the possibility to use mexidol electrophoresis for this purpose. Optimal characteristics and conditions of the procedure are described. It has been demonstrated that transcranial electrophoresis of mexidol makes it possible to improve the functional state of the neuromotor system and enhances its plasticity.

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