[Destabilization of homeostasis of organism of burn patients as a marker of sepsis development, its complications and outcome].

Aim: Detection in burn patients of markers of sepsis development, its complications and outcome.

Materials And Methods: Sera IL-6, TNF-alpha, IL-8, IL-1beta, IL-Ra, IL-18, INF-gamma, IL-10 and sTREM-1 cytokine levels of burn patients at days 3-6 and 10-17 after the burn were studied.

Results: Statistically significant cytokine parameters in blood sera that already at the early stages of the burn disease may be markers of the course severity and sepsis outcome were obtained.

[Statistical analysis in epidemiological studies of urolithiasis in the South Urals].

The aim of the study was mathematical estimation of causes and conditions of urolithiasis onset in the territory of the South Urals. The data on 18 potential risk factors were obtained from 106 sitizens of the Chelyabinsk region suffering from urolithiasis and 69 controls free of renal pathology. The data on 18 potential risk factors were obtained from 106 sitizens of the Chelyabinsk region suffering from urolithiasis and 69 controls free of renal pathology.

[Chromosomal and ontogenetic instability in sibling species of common vole (Microtus arvalis group): comparative aspects].

Populations of chromosomal sibling species Microtus arvalis and Microtus rossiaemeridionalis were studied in Ural region in habitats affected by high radiation and the control ones. Frequency of chromosome disturbances in the marrow cells and fluctuating asymmetry (FA) of 8 craniometric characters were investigated. In impact populations the frequency of chromosome aberration was very high.

[Chromosomal instability in offspring of voles in unfavorable radiation zones].

A high frequency of cells having chromosomal aberrations was shown to be preserved in the first generation of laboratory offspring of common voles, whose ancestors were captured near the East Ural radioactive track (EURT). In F2 and F3, a decrease in frequency was observed. Most likely, the cytogenetic effects observed were caused by environmental contamination with plutonium in the locality of capture.