Publications by authors named "D Iu Danilova"
Objective: To study the clinical and morphological manifestations of lung sequestration.
Material And Methods: Surgical material (lung tissue) of 18 patients (2017-2021) and 8 archival observations (1972-1994) of confirmed lung sequestration were examined. Histological staining (hematoxylin and eosin, Schiff reagent, Ziehl-Neelsen, picrofuchsin according to Van Gieson) and immunohistochemical reactions with antibodies to SMA, TTF1, CK5/6 (DAKO) were performed.
Article Synopsis
- Hyper IgE syndrome (STAT3-HIES), also known as Job's syndrome, results from mutations in the STAT3 gene, leading to chronic respiratory infections due to compromised pulmonary defense mechanisms.
- The study aimed to investigate how these STAT3 mutations affect the airway epithelium's ability to defend against infections, analyzing sputum properties and lung tissue from patients.
- Findings revealed that STAT3 deficiency disrupts critical airway functions, including mucus secretion and ciliary movement, contributing to increased infection risk and inflammation in patients with this syndrome.*
We studied the effect of molecular hydrogen H on the content of circulating endothelial cells and the macrohistological structure of the heart in rats with simulated chronic heart failure. Inhalation with 2% H was carried out repeatedly (40 min per day for 5 consecutive days) or once (40 min). Molecular hydrogen inhalations in both regimens caused a decrease in the number of circulating endothelial cells; the most pronounced effect was observed after repeated inhalations on day 14 after chronic heart failure modeling.
View Article and Find Full Text PDFMolecular hydrogen has an anti-inflammatory and cardioprotective effect, which is associated with its antioxidant properties. Erythrocytes are subjected to oxidative stress in pathologies of the cardiovascular system, which is the cause of a violation of the gas transport function of blood and microcirculation. Therefore, our aim was to investigate the effects of H inhalation on the functional states of red blood cells (RBCs) in chronic heart failure (CHF) in rats.
View Article and Find Full Text PDFWe studied the effect of molecular hydrogen (H) on the content of 2,3-diphosphoglyceric acid (2,3-DPG), ATP, malondialdehyde, and catalase activity in erythrocytes in chronic heart failure. Inhalation of 2% molecular hydrogen H was carried out for 40 min repeatedly (5 days) or once. Inhalation of H caused an increase in ATP concentration in both research groups, but was more pronounced after repeated inhalation.
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