[Use of the computer class DVK-KUVT-86 for programmed second level control with respect to pathology].

The paper deals with some experience in the programmed control of students' knowledge by constructed tests of the 2nd level using computers. According to the authors this method facilitates the development of independent logical students' thinking.

[Application of the microcomputer "Electronika BK-0010" in programmed monitoring of the degree of students' assimilation of a course in pathologic anatomy according to tests at the first level].

To optimize the programmed checking of the students' knowledge on pathological anatomy, it is feasible to use an "Elektronika BK-0010" microcomputer. In terms of the limited internal storage of the computer, a package of questions and answers to them is recorded on a magnetic tape, the microcomputer being loaded with it before each study. For maximal employment of the microcomputer's internal storage, it is expedient to use the programs based on the combined application of a text in the form of questions and computer-assisted processing of the students answers.

[Electron microscopy study of pathological collagen fibril formation in systemic scleroderma].

Electron microscopy of the skin biopsies from patients with systemic sclerodermia revealed the pathologic alterations of cellular and intracellular structures. The disease is characterized by focal lysis of nuclear, organoid and cytoplasmic membranes of the fibroblastic cells with the most essential alteration of cell plasmalemma. The cellular fragments (parts of cytoplasma, cisterns of the rough endoplasmic reticulum, mitochondria, nuclear debris) are found between the extracellular bundles of collagen fibrils.

[Formation of collagen fibrils in the synovial membrane in rheumatoid arthritis (electron microscope study)].

As demonstrates investigation of the synovial membrane biopsies obtained in patients suffering from rheumatoid arthritis, excessive formation of collagenous fibrillae results from participation, in this process, of activated synoviocytes B, pericytes and fibroblasts capable to intensify secretion and synthesis of tropocollagen. Aggregation of tropocollagen molecules into the collagenous fibrillae occurs in the areas where the inflammation acquires a chronic form where the cellular detritus is accumulated and where immune complexes are deposited. In the places mentioned, together with assembling normal collagenous fibrillae certain pathological fibrillar forms are observed, such as: fibrillae with an increased diameter, fibrillae with a changeable optic density of transversal streakness, those deprived of it, as well as segmentary scrap of fibrillo-formation.