Impacts of intellectual property provisions in trade treaties on access to medicine in low and middle income countries: a systematic review.

Background: We present a systematic review describing ex-ante and ex-post evaluations of the impacts of intellectual property provisions in trade treaties on access to medicine in low and middle income countries. These evaluations focused on multilateral and bilateral trade agreements. We ascertained which IP provisions impacting access to medicines were the focus of these evaluations.

Dementia: a word to be forgotten.

A rationale is presented for the elimination of the word dementia as a diagnostic term. It is viewed as a generalization that is pejorative and harmful based on historical and current patient, caregiver, and physician perspectives. Suggestions for more meaningful and nonstigmatizing terminology are offered.

Exploring the role of complementary and alternative medicine in public health practice and training.

Objectives: Consumer use of complementary and alternative medicine (CAM) in the United States continues to expand. Although conventional medicine has responded actively, the response from public health has been far less pronounced. To examine the potential for integrating CAM into public health contexts, an exploratory survey was conducted.

A new frameshift mutation encoding a truncated amelogenin leads to X-linked amelogenesis imperfecta.

The amelogenin proteins are the most abundant organic components of developing dental enamel. Their importance for the proper mineralization of enamel is evident from the association between previously identified mutations in the X-chromosomal gene that encodes them and the enamel defect amelogenesis imperfecta. In this investigation, an adult male presenting with a severe hypoplastic enamel phenotype was found to have a single base deletion at the codon for amino acid 110 of the X-chromosomal 175-amino acid amelogenin protein.