Publications by authors named "D I Lampropoulou"

Article Synopsis
  • The study explores the use of FeO and FeO Au nanoparticles as hyperthermic agents to treat breast cancer by increasing temperatures beyond normal levels, focusing on their cytotoxic effects on cancer cells compared to normal cells.
  • Researchers tested these nanoparticles on the SK-BR-1 breast cancer cell line and assessed toxicity and the expression of proliferation markers (Ki-67, TOP2A, TPX2) using real-time PCR.
  • Results indicated that FeO Au nanoparticles were more toxic to cancer cells than FeO, reducing the expression of proliferation markers in the cancer cells, suggesting that surviving cells were not actively dividing, highlighting the potential of these nanoparticles in cancer treatment.
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Humans, led by their eternal wish to explore the unknown, have always wanted to perfect their diving skills and conquer the sea world. The adverse conditions experienced by divers brought about medical problems and a new field of medicine. Diving medicine serves the identification, treatment, and precautions against illnesses that are related to diving activities.

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Hyperthermia has the potential to damage cancerous tissue by increasing the body temperature. However, targeting cancer cells whilst protecting the surrounding tissues is often challenging, especially when implemented in clinical practice. In this direction, there are data showing that the combination of nanotechnology and hyperthermia offers more successful penetration of nanoparticles in the tumor environment, thus allowing targeted hyperthermia in the region of interest.

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The incidence of thyroid metastases among patients suffering from primary colorectal cancer is rare, and only a few cases have been described in the literature. As these metastases are usually asymptomatic, they most frequently present as incidentalomas on follow-up imaging. Hereby, we present and discuss an interesting case of metastatic sigmoid adenocarcinoma of the thyroid gland, diagnosed and treated at our institution.

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