Publications by authors named "D I Groves"
Many viruses are pleomorphic in shape and size, with pleomorphism often thought to correlate with infectivity, pathogenicity, or virus survival. For example, influenza and respiratory syncytial virus particles range in size from small spherical virions to filaments reaching many micrometers in length. We have used a pressure vessel model to investigate how the length and width of spherical and filamentous virions can vary for a given critical stress and fluorescence super-resolution microscopy along with image analysis tools to fit imaged influenza viruses to the model.
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- Major health conditions like cancer, coronary heart disease, dementia, and stroke significantly impact morbidity and mortality rates in England, with a focus on their economic burden in 2018.
- The study utilized patient data from the Clinical Practice Research Datalink and the English Longitudinal Study on Ageing to calculate costs associated with healthcare, care services, and productivity losses for these diseases.
- In 2018, the total costs were estimated at £18.9 billion for cancer, £12.7 billion for coronary heart disease, £11.7 billion for dementia, and £8.6 billion for stroke, with projections showing substantial increases in costs by 2050, particularly for dementia, which could see
Article Synopsis
- This study distinguishes between nondilated left ventricular cardiomyopathy (NDLVC) and dilated cardiomyopathy (DCM) by using cardiac magnetic resonance (CMR) and genetic testing on 462 patients across four centers.
- Findings showed that NDLVC patients had better heart function and a higher prevalence of specific genetic variants compared to those with DCM, highlighting significant differences in their conditions.
- The presence of septal late gadolinium enhancement and other factors like LV dilatation, age, and arrhythmias were identified as strong predictors for serious cardiac events, such as sudden cardiac death.