The use of intraoperative fluoroscopy in surgery produces scattered radiation that can expose all operating room personnel to measurable and, in some cases, substantial radiation doses. The goal of this work is to assess and document potential radiation doses to various staff positions in a simulated standard operating room environment. Adult-sized mannequins wearing standard lead protective aprons were placed at seven positions around large and small BMI cadavers.
View Article and Find Full Text PDFOral life history narratives are a promising method to promote person-centered values of personhood and belonging. This project used resident oral history interviews to educate staff members in an assisted-living setting about personhood. A single group pre-post test design evaluated impacts on 37 staff members to assess their use of resident videotaped oral history interviews and impacts on their perceived knowledge of residents.
View Article and Find Full Text PDFTissue-specific transcription factors forming the regulatory cascades which determine the specification and differentiation of epithelial cells during embryogenesis, play the central role in the control of functional and morphological properties of different cell types. Hepatocyte nuclear factors (HNFs) network is one of the most investigated tissue-specific regulatory systems which controls the specification and maintenance of differentiation of several epithelial cell types. Nuclear receptor HNF4α is one of the central elements of this regulatory network in the liver.
View Article and Find Full Text PDFBiochemistry (Mosc)
May 2008
Dedifferentiation and epithelial-mesenchymal transition are important steps in epithelial tumor progression. A central role in the control of functional and morphological properties of different cell types is attributed to tissue-specific transcription factors which form regulatory cascades that define specification and differentiation of epithelial cells during embryonic development. The main principles of the action of such regulatory systems are reviewed on an example of a network of hepatocyte nuclear factors (HNFs) which play a key role in establishment and maintenance of hepatocytes--the major functional type of liver cells.
View Article and Find Full Text PDFJ Environ Radioact
August 2008
The goal of this review is to draw attention to an opportunity for the use of cosmogenic (22)Na for dating young surface and underground waters. After 1961 when a significant quantity of (22)Na was released into the environment as a result of nuclear weapon tests, its concentrations in river waters were greatly increased, and a return to natural (cosmogenic) levels took until the mid-1980s. The studies made during this non-steady-state period showed that the one-box model for freshwater basin correctly describes the experimental data.
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